2019


Synthesis and biological evaluation of aryl phosphoramidate prodrugs of fosfoxacin and its derivatives.

Mathilde munier, Denis Tritsch, Didier lièvremont, Michel Rohmer, Catherine Grosdemange-Billiard

Bioorg. Chem 2019, 89, 103012


2017


Adaptation in toxic environments: comparative genomics of loci carrying antibiotic resistance genes derived from acid mine drainage waters.

Arsène-Ploetze F., Chiboub O., Lièvremont D., Farasin J., Freel KC., Fouteau S. & Barbe V.

Environ Sci Pollut Res, 2017, 2, 1470-1483 – DOI: 10.1007/s11356-017-0535-8


Synthesis and biological evaluation of phosphate isosters of fosmidomycin andanalogs as inhibitors of Escherichia coli and Mycobacterium smegmatis 1-deoxyxylulose 5-phosphate reductoisomerases.

Munier M., Tritsch D., Krebs F., Esque J., Hemmerlin A., Rohmer M., Stote RH. & Grosdemange-Billiard C.

Bioorg Med Chem., 2017, 25, 684-689 – DOI: 10.1016/j.bmc.2016.11.040


2016


Identification and mode of formation of hopanoid nitriles in archaeological soils.

Adam P, Schaeffer P, Schmitt G, Bailly L, Courel B, Fresnais M, Fossurier  &  Rohmer M.

Org. Geochem., 2016, 91, 100-108 – DOI: 10.1016/j.orggeochem.2015.10.013 

 


2015


Optimization of antifungal production by an alkaliphilic and halotolerant actinomycete, Streptomyces sp. SY-BS5, using response surface methodology.

Souagui Y., Tritsch D., Grosdemange-Billiard C. & Kecha M.

J. Myc. Med., 2015, 2, 108-105 – DOI: 10.1016/j.mycmed.2014.12.004


Flavonoids: true or promiscuous inhibitors of enzyme? The case of deoxyxylulose phosphate reductoisomerase.

Tritsch D., Zinglé C., Rohmer M. & Grosdemange-Billiard C.

Bioorg. Chem., 2015, 59, 140-144 – DOI: 10.1016/j.bioorg.2015.02.008

 


C-35 hopanoid side chain biosynthesis: Reduction of ribosylhopane into bacteriohopanetetrol by a cell-free system derived from Methylobacterium organophilum.

Bodlenner A., Liu W., Hirsch G., Schaeffer P., Blumenberg M., Lendt R., Tritsch D., Michaelis W. & Rohmer M.

ChemBioChem., 2015, 16, 1764-1770 – DOI: 10.1002/cbic.201500021


Biosynthesis of monoterpene scent compounds in roses.

Magnard JL, Roccia A, Caissard JC, Vergne P, Sun PL, Hecquet R, Dubois A, Hibrand-Saint Oyant L, Jullien F, Nicole F, Raymond O, Huguet S, Baltenweck R, Meyer S, Claudel P, Jeauffre J, Rohmer M, Foucher, Hugueney P, Bendahmane M & Baudino S.

Science, 2015, 349, 81-83 – DOI: 10.1126/science.aab0696


Hemisynthesis of deuteriated adenosylhopane and conversion into bacteriohopanetetrol by a cell-free system from Methylobacterium organophilum.

Liu W., Bodlenner A. & Rohmer M.

Org. Bio. Med. Chem. 2015, 13, 3393-3405 – DOI: 10.1039/c4ob02560a


Thiomonas sp.CB2 is able to degrade urea and promote toxic metal precipitation in acid mine drainage waters supplemented with urea.

Farasin J., Andres J., Casiot C., Barbe V., Faerber J., Halter D., Heintz D., Koechler S, Lièvremont D., Lugan R., Marchal M., Plewniak F., Seby F., Bertin PN. & Arsène-Ploetze F.

Front. Microbiol. 2015, 6, 993 – DOI: 10.3389/fmicb.2015.00993


Constitutive arsenite oxidase expression detected in arsenic-hypertolerant Pseudomonas xanthomarina S11.

Koechler S., Arsene-Ploetze F., Brochier-Armanet C., Goulhen-Chollet F., Heinrich-Salmeron A., Jost B, Lièvremont D., Philipps M., Plewniak F., Bertin PN. & Lett M-C.

Res. Microbiol. 2015, 166, 205-214 – DOI: 10.1016/j.resmic.2015.02.010


2014


Catechol-rhodanine derivatives: specific and promiscuous inhibitors of Escherichia coli deoxyxylulose phosphate reductoisomerase (DXR).

Zinglé C., Tritsch D., Grosdemange-Billiard C. & Rohmer M.

Bioorg. Med. Chem. 2014, 22, 3713-3719 – DOI:  http://dx.doi.org/10.1016/j.bmc.2014.05.004


Ribosylhopane, a novel bacterial hopanoid, as precursor of C-35 bacteriohopanepolyols in Streptomyces coelicolor A3(2).

Liu W., Sakr E., Schaeffer P., Talbot HM., Donisi J., Hartner T., Kannenberg E., Takano E. & Rohmer M.

Chem. Bio Chem., 2014, 15, 2156-2161 – DOI: 10.1002/cbic.201402261


Dibenzyl Phosphate.

Munier M. & Grosdemange-Billiard C.

e-EROS ,2014 DOI: 10.1002/047084289X.rn01794


Profiling of defense responses in Escherichia coli treated with fosmidomycin.

Hemmerlin A., Tritsch D., Hammann P., Rohmer M. & Bach TJ.

Biochim. 2014, 99, 54-62 – DOI: 10.1016/j.biochi.2013.11.008


S-Carvone suppresses cellulase-induced capsidiol production in Nicotiana tabacum by interfering with protein isoprenylation.

Huchelmann A., Gastaldo C., Veinante M., Zeng Y., Heintz D., Tritsch D., Schaller H., Rohmer M., Bach TJ. & Hemmerlin A.

Plant Physiol, 2014164, 935-950 – DOI: 10.1104/pp.113.232546